Nebraska duo eyes end to costly swine diseases

Two University of Nebraska–Lincoln researchers have received $1 million in grant funding to continue research.

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Husker researchers on cusp of swine industry protection

Researchers Hiep Vu and Haiyan Sun are working to develop a broad coverage PRRSV vaccine to help sustainable pork production.

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NUtech Ventures honors UNL faculty

NUtech Ventures recognized University of Nebraska-Lincoln innovators and their promising technologies during a recent luncheon.

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The 2017 Junior Faculty Excellence in Research award

Dr. Hiep Vu was as a recipient of the Junior Faculty Excellence in Research award presented by The Agricultural Research Division (ARD).

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Research Interest

The Vu Laboratory is interested in translational research that helps promote animal health and well-being. The overarching goal of is to develop effective intervention strategies to control viral diseases in animals. Currently, the lab is devoted to study three major swine viruses: porcine reproductive and respiratory syndrome virus (PRRSV), swine influenza virus (SIV) and African swine fever virus (ASFV). The research topics include: (i) characterization of host immune responses to natural infection or vaccination, (ii) identification of viral proteins and/or epitopes capable of eliciting protective immunity and (iii) rationale design of safe and efficacy vaccine immunogens.

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Principal Investigator

Dr. Hiep Vu

Dr. Hiep Vu has a passionate interest in swine virology. He completed his bachelor’s degree in Veterinary Medicine in 2005 from Nong Lam University, Ho Chi Minh City, Vietnam. After that, he pursued his graduate training at the School of Veterinary Medicine and Biomedical sciences, University of Nebraska Lincoln (UNL), where he received his Master and PhD in 2007 and 2013, respectively. Dr. Vu is now an Assistant Professor at the Nebraska Center for Virology and Department of Animal Science, UNL.

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Chaudhari J., Nguyen NT, Vu H., 2022. Identification of cryptic promoter activity in cDNA sequences corresponding to PRRSV 5’untraslated region and transcription regulatory sequences. Viruses 14.2 (2022): 400. PMID: 8874549. Download PDF.

Luong Q.H., Lai T.L.H., Do L.D., Ha X.B., Nguyen V.G. and Vu H.L*., 2021. Differential antibody responses in sows and finishing pigs naturally infected with African swine fever virus under field conditions. Virus Res. 2022 Jan 2;307:198621. PMID:34799123. Download PDF.

Chaudhari J., Liew CS, Riethoven JJ, Sillman S., and Vu H.*, 2021. Porcine reproductive and respiratory syndrome virus infection upregulates negative immune regulators and T cell exhaustion markers. J Virol. 2021 Oct 13;95(21):e0105221. PMID: 34379512. Download PDF.

Truong, Q.L., Nguyen, T.H., Nguyen, T.L., Shi, J., Vu, H., Lai, T.L.H., Nguyen, V.G., 2021. Genome sequence of a virulent African swine fever virus isolated in 2020 from a domestic pig in Northern Vietnam. Microbiology Resource Announcements 10.19 (2021): e00193-21. PMID: 8142564. Download PDF.

Chaudhari J., and Vu H*. Porcine Reproductive and Respiratory Syndrome Virus Reverse Genetics and the Major Applications. Viruses. 2020 Oct 31;12(11). Review. PMID: 33142752. Download PDF.

Danh Cong Lai

Visiting Scholar

Jayesh Chaudhari

Post-Doctoral Associate

The Nguyen

Visiting Scholar

Hung Luong

Visiting Scholar

Sushmita Kumari

PhD Student